They can run into each other. I imagine Vanessa will freak out pretty hard at first but will chill out a little when she figures out he's not actually a rotting corpse. That said, if he got himself into trouble or something around the Dead District area she could probably help him out. Maybe show him the ropes of getting by without a home or something, or just give him a place to sleep for a night because that poor kid, jeez.

Vanessa probably wouldn't be scavenging metal from outside, because the metal she uses needs to be within a certain range of purity to be effective. Also, cause she swallows it to use it and ew.

Still, they could at least run into each other and maybe compare notes or something.